Definition: Gonadal failure occurs when sufficient amounts of sex hormones to suppress LH and FSH to normal levels are not produced. Failure of the gonads may be caused by both congenital and developmental disorders, certain infections including mumps, trauma, surgery, toxic exposure, and cancer treatments including chemotherapy and radiation treatment. Characteristics of gonadal failure are low levels of sex hormones and increased levels of LH and FSH.Common Misspellings: gonodol gonadolif(zSbL
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